I wrote a review on the #1 version of the formula about how these little GI renew formulas saved me from colon cancer. You can see it there but the gist of it is, I was headed for disaster. I wasn’t perfect with my diet but I’ve always taken the GI herbs, between the #1, #2 as appropriate at least once a day before bed. I had a long over due colonoscopy, like 10 years over due when I was warned not to go longer than 5 years based on my personal history with the scopes, and yet what should have been bad news, turns out incredible- I was squeaky clean! Not 1 polyp in sight! I credit the herbs- no doubt in my mind! Beyond grateful!