I was told by my doctor not to try these herbal products. I have CKD. Since I took these products, my CKD went from a stage three to stage two. My kidney doctor had mentioned to me not to take these products that they were not FDA approved. I told him that the FDA approved medication‘s have a ton of side effects and I want to go this route. When I went into my office visit. He told me that my kidney functions were good, and not to come back and less they dropped. I am a true believer of these products.